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Publication : Differently shaped spines increase in the posterodorsal medial amygdala of oxytocin knockout female mice.

First Author  Becker RO Year  2015
Journal  Neurosci Res Volume  101
Pages  53-6 PubMed ID  26163772
Mgi Jnum  J:239802 Mgi Id  MGI:5829654
Doi  10.1016/j.neures.2015.07.001 Citation  Becker RO, et al. (2015) Differently shaped spines increase in the posterodorsal medial amygdala of oxytocin knockout female mice. Neurosci Res 101:53-6
abstractText  The posterodorsal medial amygdala (MePD) is a sexually dimorphic area in the social behavior neural network, with high concentration of oxytocin (OT) receptors. Wild type (WT) and OT knockout (OTKO) females were studied in proestrus, and Golgi-impregnated spines in the MePD were classified. Results show that the OTKO group has increased density of thin, mushroom, and stubby/wide spines when compared to the WT (p<0.01 in all cases). These data indicate that OT is an important synaptic modulator in the MePD, a finding that is likely involved with the display of the female sexual behavior.
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