First Author | Becker RO | Year | 2015 |
Journal | Neurosci Res | Volume | 101 |
Pages | 53-6 | PubMed ID | 26163772 |
Mgi Jnum | J:239802 | Mgi Id | MGI:5829654 |
Doi | 10.1016/j.neures.2015.07.001 | Citation | Becker RO, et al. (2015) Differently shaped spines increase in the posterodorsal medial amygdala of oxytocin knockout female mice. Neurosci Res 101:53-6 |
abstractText | The posterodorsal medial amygdala (MePD) is a sexually dimorphic area in the social behavior neural network, with high concentration of oxytocin (OT) receptors. Wild type (WT) and OT knockout (OTKO) females were studied in proestrus, and Golgi-impregnated spines in the MePD were classified. Results show that the OTKO group has increased density of thin, mushroom, and stubby/wide spines when compared to the WT (p<0.01 in all cases). These data indicate that OT is an important synaptic modulator in the MePD, a finding that is likely involved with the display of the female sexual behavior. |