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Allele : Prkcg<tm1Stl> protein kinase C, gamma; targeted mutation 1, Susumu Tonegawa

Primary Identifier  MGI:1857237 Allele Type  Targeted
Attribute String  Null/knockout Gene  Prkcg
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin resistance cassette replaced 2.5kb of sequence containing the exon that encodes the nucleotide binding domain. Northern blot analysis of total brain RNA demonstrated that homozygous mutant mice lack normal transcripts. Western blot analysis of total brain protein did not detect the protein in homozygous mutant mice.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • PKCgamma-KO,
  • PKCgamma-KO
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

45 Publication categories