| First Author | Seiler KP | Year | 1998 |
| Journal | Infect Immun | Volume | 66 |
| Issue | 9 | Pages | 4557-9 |
| PubMed ID | 9712820 | Mgi Jnum | J:49413 |
| Mgi Id | MGI:1277458 | Doi | 10.1128/iai.66.9.4557-4559.1998 |
| Citation | Seiler KP, et al. (1998) E and P selectins are not required for resistance to severe murine lyme arthritis. Infect Immun 66(9):4557-9 |
| abstractText | Borrelia burgdorferi-induced arthritis in mice is characterized by tendonitis, synovitis, and inflammatory-cell infiltrate, predominantly of neutrophils. Because genetic deficiency in E and P selectins results in delayed recruitment of neutrophils to sites of inflammation, mice with this deficiency were tested for their response to infection with B. burgdorferi. E and P selectins were not required for the control of B. burgdorferi numbers, nor did deficiency in E and P selectins result in alteration of arthritis severity. |
