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Allele : Syt1<tm1Sud> synaptotagmin I; targeted mutation 1, Thomas C Sudhof

Primary Identifier  MGI:1857252 Allele Type  Targeted
Attribute String  Null/knockout Gene  Syt1
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  false Is Wild Type  false
molecularNote  A 5' portion of the exon encoding amino acids 270 through 308 and the preceding intron were replaced with a neomycin selection cassette. In addition to the coding sequence, the intron acceptor site was deleted. Lysates derived from the brains of homozygous mice were shown to contain less than 5% of the amount of a truncated form of the encoded protein compared to controls by immunoblotting.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Syt-,
  • Syt-
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

46 Publication categories