Primary Identifier | MGI:1857424 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | E2f1 |
Transmission | Germline | Strain of Origin | 129S4/SvJae |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Part of exon 3, intron 3 and exon 4 were replaced with a neomycin cassette. These sequences encode residues encoding the leucine zipper and those critical for DNA binding. Northern blot analysis did not detect a transcript made from this allele in fibroblasts isolated from homozygous embryos. |