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Allele : E2f1<tm1Meg> E2F transcription factor 1; targeted mutation 1, Michael E Greenburg

Primary Identifier  MGI:1857424 Allele Type  Targeted
Attribute String  Null/knockout Gene  E2f1
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  false Is Wild Type  false
molecularNote  Part of exon 3, intron 3 and exon 4 were replaced with a neomycin cassette. These sequences encode residues encoding the leucine zipper and those critical for DNA binding. Northern blot analysis did not detect a transcript made from this allele in fibroblasts isolated from homozygous embryos.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • E2f1-,
  • E2f1-,
  • E2F-1<->,
  • E2F-1<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

0 Driven By

101 Publication categories