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Allele : Ahr<tm1Bra> aryl-hydrocarbon receptor; targeted mutation 1, Christopher A Bradfield

Primary Identifier  MGI:1857427 Allele Type  Targeted
Attribute String  Null/knockout Gene  Ahr
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin selection cassette replaced a genomic fragment containing exon 2, which encodes the basic-HLH domain essential for dimerization and DNA binding. Western blot analysis on liver cytosol demonstrated that the protein was not detectable in homozygous mice.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • AhrKO,
  • Ahr<->,
  • Ahr<->,
  • AhrKO
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

7 Carried By

0 Driven By

160 Publication categories