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Allele : Bcl2<tm1Mpin> B cell leukemia/lymphoma 2; targeted mutation 1, Max-Planck-Institute for Neurobiology

Primary Identifier  MGI:1857430 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Bcl2
Transmission  Germline Strain of Origin  129S2/SvPas
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 2 was disrupted by the insertion of a lacZ gene and neomycin selection cassette. Western blot analysis on hippocampal lysates from homozygous mice demonstrated that no stable Bcl2 protein was made from this allele. A beta-galactosidase protein was produced from this allele under the control of the endogenous promoter.
  • mutations:
  • Insertion
  • synonyms:
  • bcl-2 -,
  • bcl-2 -
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

14 Publication categories