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Allele : Htr2c<tm1Jul> 5-hydroxytryptamine (serotonin) receptor 2C; targeted mutation 1, David Julius

Primary Identifier  MGI:1857439 Allele Type  Targeted
Attribute String  Null/knockout Gene  Htr2c
Transmission  Germline Strain of Origin  129S/Sv
Is Recombinase  false Is Wild Type  false
description  ES cell line = D3 (129S2/SvPas) or J1 (129S4/SvJae).
molecularNote  Insertion of a nonsense mutation into exon 5 of the gene resulted in the introduction of a stop codon within the fifth putative transmembrane segment of the receptor and in the elimination of the carboxy-terminal half of the protein.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • 5-HT2cR-deficient,
  • 5-HT2cR-deficient
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

Trail: Allele

0 Driven By

42 Publication categories

Trail: Allele