First Author | Wang YP | Year | 2002 |
Journal | Nat Neurosci | Volume | 5 |
Issue | 9 | Pages | 831-2 |
PubMed ID | 12195432 | Mgi Jnum | J:78708 |
Mgi Id | MGI:2385969 | Doi | 10.1038/nn911 |
Citation | Wang YP, et al. (2002) Development of normal retinal organization depends on Sonic hedgehog signaling from ganglion cells. Nat Neurosci 5(9):831-2 |
abstractText | The adult retina is organized into three cellular layers--an outer photoreceptor, a middle interneuron and an inner retinal ganglion cell (RGC) layer. Although the retinal pigment epithelium (RPE) and Muller cells are important in the establishment and maintenance of this organization, the signals involved are unknown. Here we show that Sonic hedgehog signaling from RGCs is required for the normal laminar organization in the vertebrate retina. |