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Publication : Tumor necrosis factor alpha plays a role in the acceleration of atherosclerosis by Chlamydia pneumoniae in mice.

First Author  Campbell LA Year  2005
Journal  Infect Immun Volume  73
Issue  5 Pages  3164-5
PubMed ID  15845526 Mgi Jnum  J:97619
Mgi Id  MGI:3575949 Doi  10.1128/IAI.73.5.3164-3165.2005
Citation  Campbell LA, et al. (2005) Tumor necrosis factor alpha plays a role in the acceleration of atherosclerosis by Chlamydia pneumoniae in mice. Infect Immun 73(5):3164-5
abstractText  The role of tumor necrosis factor alpha (TNF-alpha) in Chlamydia pneumoniae atherogenesis was evaluated in TNF-alpha p55 receptor-deficient C57BL/6J mice fed a high-fat/high-cholesterol diet. No acceleration of atherosclerotic lesion development was observed in infected mice compared to uninfected mice, indicating that TNF-alpha plays a role in the acceleration of atherosclerosis by C. pneumoniae.
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