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Allele : Rara<tm1Ipc> retinoic acid receptor, alpha; targeted mutation 1, Pierre Chambon

Primary Identifier  MGI:1857622 Allele Type  Targeted
Attribute String  Null/knockout Gene  Rara
Transmission  Germline Strain of Origin  129S2/SvPas
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin cassette was inserted into exon 8, which encodes the common receptor region B. This disruption is predicted to prevent the synthesis of all Rara isoforms. RNAase protection analysis of homozygous E13.5 embryos failed to detect wild type RNA transcripts and immunoblot analysis failed to detect protein in in extracts from homozygous E13.5 embryos.
  • mutations:
  • Insertion
  • synonyms:
  • Aalpha,
  • Rara-,
  • Rara-,
  • RARalpha<->,
  • Aalpha,
  • RARalpha<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

35 Publication categories