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Allele : Prrx2<tm1Hubr> paired related homeobox 2; targeted mutation 1, Hubrecht Institute

Primary Identifier  MGI:1857641 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Prrx2
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A lacZ/PGK-Hygro cassette was inserted just upstream of the homeobox domain, such that the lacZ encoding sequence is in-frame. The allele is expected to express the first 88 amino acids of the Prrx2 protein, fused to the Beta-gal protein, in a pattern identical to that of the Prrx2 gene. The absence of both the homeodomain and the aristaless domain make it unlikely that the protein retains any endogenous biochemical activity.
  • mutations:
  • Insertion
  • synonyms:
  • Prx2 -,
  • Prx2 -
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories