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Allele : Met<tm1Cbm> met proto-oncogene; targeted mutation 1, Carmen Birchmeier
Primary Identifier  MGI:1857655 Allele Type  Targeted
Attribute String  Null/knockout Gene  Met
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin selection cassette replaced an exon encoding the invariant lysine 1108. RNAse protection analysis revealed that normal levels of a transcript lacking nucleotides 3254-3334 is produced from this allele, but no protein activity is detectable in an in vitro auto-kinase assay.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • met<->,
  • met<->,
  • c-Met -,
  • c-Met -
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

13 Publication categories





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