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Allele : Alx1<tm1Crm> ALX homeobox 1; targeted mutation 1, Benoit de Crombrugghe

Primary Identifier	MGI:1857553	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Alx1
Transmission	Germline	Strain of Origin	129S7/SvEvBrd-Hprt1<+>
Is Recombinase	false	Is Wild Type	false

molecularNote

A neomycin resistance cassette replaced a 7.4kb genomic fragment containing exons 1-3. These sequences encode two thirds of the protein including the homeodomain and the potential translation initiation site.

mutations:
Intragenic deletion,
Insertion

cellLines:
Not Specified

synonyms:
Cart1<->,
Cart1<->

earliestPublication:
Zhao Q, et al. (1996) Prenatal folic acid treatment suppresses acrania and meroanencephaly in mice mutant for the Cart1 homeobox gene. Nat Genet 13(3):275-83

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

7 Publication categories

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