Primary Identifier | MGI:1857489 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Wnt3a |
Transmission | Germline | Strain of Origin | 129S1/Sv-Oca2<+> Tyr<+> Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The insertion of neomycin selection cassette into exon 3 introduced a stop codon that results in a truncated peptide approximately one-third the normal size. Transcription of the targeted loci was detected in homozygous mutant embryos via in situ hybridization. |