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Allele : Lats1<tm1Tx> large tumor suppressor; targeted mutation 1, Tian Xu
Primary Identifier  MGI:1857685 Allele Type  Targeted
Attribute String  Null/knockout Gene  Lats1
Transmission  Germline Strain of Origin  129S2/SvPas
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin resistance cassette replaced sequence encoding amino acids 756 - 1130 of the protein. Immunoprecipitation and Western blots of embryonic fibroblasts lysates from homozygous mutant mice showed no detectable protein for the targeted gene.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Lats1<->,
  • Lats1<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

8 Publication categories





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