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Allele : Vcan<Tg(Hoxa1)1Chm> versican; transgene insertion 1, Corey H Mjaatvedt

Primary Identifier  MGI:1857689 Allele Type  Transgenic
Attribute String  Null/knockout, Reporter Gene  Vcan
Inheritance Mode  Recessive Strain of Origin  C57BL/6J or CBA
Is Recombinase  false Is Wild Type  false
molecularNote  The transgene consisted of 3.5kb of the Hoxa1 regulatory region gene with a lacZ reporter sequence. The transgene inserted into intron 7 and separates exons 7 and 8, which code for the two chondroitin sulfate binding domains. RT-PCR analysis detected truncated mRNA transcripts in homozygous embryos. None of the alternative splice forms of the gene are detected in hearts from homozygous mice.
  • mutations:
  • Insertion
  • synonyms:
  • hdf,
  • Vcan<hdf>,
  • Cspg2<hdf>,
  • hdf, heart defect,
  • hdf, heart defect,
  • Cspg2<hdf>,
  • Vcan<hdf>,
  • hdf
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

17 Publication categories