| Primary Identifier | MGI:1857694 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Smad2 |
| Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A neomycin cassette replaced 2.5 kb of the gene, including the sequence that encodes the carboxy-terminal 86 amino acids of the protein. Southern blots and PCR analysis indicated that the mutation was passed on to the agouti offspring of the chimeras. |