|  Help  |  About  |  Contact Us

Allele : Flt1<tm1Jrt> FMS-like tyrosine kinase 1; targeted mutation 1, Janet Rossant

Primary Identifier  MGI:1857717 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Flt1
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A LacZ-neomycin resistance cassette replaced sequences that encode the signal peptide. The authors predict this is a null allele because the translation start site is removed and reinitiation at the first two downstream Kozak sequences would result in out-of-frame translated products.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Flt1<lacZ>,
  • Flt1<lacZ>,
  • Flt-1<lacZ>,
  • flt-1<lcz>,
  • VEGFR1-lacZ,
  • Flt-1<->,
  • flt-1<lcz>,
  • Flt-1<->,
  • Flt-1<lacZ>,
  • VEGFR1-lacZ
Quick Links:
 
Quick Links:
 

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

37 Publication categories