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Allele : Gjb1<tm1Kwi> gap junction protein, beta 1; targeted mutation 1, Klaus Willecke

Primary Identifier  MGI:1857927 Allele Type  Targeted
Attribute String  Null/knockout Gene  Gjb1
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin resistance cassette was inserted into exon 2 of the gene, resulting in a stop codon 90 nucleotides after the translational start and a new start codon 15 base pairs further downstream. Northern blots of total liver RNA from homozygous mutant mice showed no detectable transcript for the gene.
  • mutations:
  • Insertion
  • synonyms:
  • Cx32-,
  • Cx32-
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

87 Publication categories