| Primary Identifier | MGI:1857934 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Prkdc |
| Transmission | Germline | Strain of Origin | 129S1/Sv-Oca2<+> Tyr<+> Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Half of exon 3 and part of intron 3 was replaced with a PGK-neo cassette via homologous recombination. RT-PCR showed deletion of exons 1-4 in homozygous mutant animals and Western blot failed to detect protein product. In vitro kinase assay of fibroblasts from homozygous mutant animals was negative for kinase activity. |
