|  Help  |  About  |  Contact Us

Allele : Pten<tm1Mak> phosphatase and tensin homolog; targeted mutation 1, Tak W Mak

Primary Identifier  MGI:1857937 Allele Type  Targeted
Attribute String  Null/knockout Gene  Pten
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin selection cassette replaced a genomic fragment containing the splice donor site of exon 2 and exons 3-5. RT-PCR analysis on liver RNA from heterozygous mice demonstrated that an aberrant, smaller transcript was made from this allele, but no functional protein is predicted to be made.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • mPTEN-,
  • Pten-,
  • mPTEN<3-5>,
  • mPTEN-,
  • Pten-,
  • mPTEN<3-5>
Quick Links:
 
Quick Links:
 

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

27 Publication categories