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Allele : Msh2<tm1Mak> mutS homolog 2; targeted mutation 1, Tak W Mak

Primary Identifier  MGI:1857940 Allele Type  Targeted
Attribute String  Null/knockout Gene  Msh2
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin resistance cassette was inserted in an antisense orientation in an exon of the gene that corresponded to exon 11 of the human gene, resulting in the deletion of 68 bp (1959 - 2026). Western blots of protein extracts from tail fibroblasts of homozygous mutant mice showed no detectable protein expressed for the targeted gene.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • MSH2-,
  • MSH2-
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

0 Driven By

61 Publication categories