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Allele : Pms2<tm1Lisk> PMS1 homolog2, mismatch repair system component; targeted mutation 1, Michael Liskay

Primary Identifier	MGI:1857947	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Pms2
Transmission	Germline	Strain of Origin	129S2/SvPas
Is Recombinase	false	Is Wild Type	false

molecularNote

A neomycin cassette was inserted into exon 2, replacing a highly conserved region of the gene. Protein was not detectable by Western analysis in fibroblast cultures from homozygous mutant animals.

mutations:
Insertion,
Intragenic deletion

cellLines:
Not Specified

synonyms:
Pms2<->,
Pms2<->

earliestPublication:
Baker SM, et al. (1995) Male mice defective in the DNA mismatch repair gene PMS2 exhibit abnormal chromosome synapsis in meiosis. Cell 82(2):309-19

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

42 Publication categories

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