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Allele : Apc<tm1Rak> APC, WNT signaling pathway regulator; targeted mutation 1, Raju Kucherlapati

Primary Identifier  MGI:1857951 Allele Type  Targeted
Attribute String  Null/knockout Gene  Apc
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin resistance cassette was inserted into exon 15 at a site corresponding to codon 1638. This mutation is predicted to result in a truncated protein. RT-PCR analysis detected a mutated transcript produced from this allele, but a truncated protein was not consistently detected by Western blot analysis.
  • mutations:
  • Insertion
  • synonyms:
  • Apc1638N,
  • APC1638,
  • APC<1638N>,
  • APC<1638N>,
  • Apc1638N,
  • APC1638
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

4 Carried By

0 Driven By

111 Publication categories