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Allele : Bmp8a<tm1Blh> bone morphogenetic protein 8a; targeted mutation 1, Brigid L Hogan

Primary Identifier  MGI:1857953 Allele Type  Targeted
Attribute String  Null/knockout Gene  Bmp8a
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  An 8 kb genomic fragment containing exons 4-6 was replaced with a neomycin selection cassette. In situ hybridization experiments on spermatids in testes of homozygous male mice demonstrated that an aberrant transcript is produced from this allele, but no functional protein is predicted to be produced from this allele since the majority of the coding sequences were deleted.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Bmp8a<tm1>,
  • Bmp8a<tm1>,
  • Bmp8a-,
  • Bmp8a-
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories