| Primary Identifier | MGI:1857954 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Bmp8b |
| Transmission | Germline | Strain of Origin | 129/Sv |
| Is Recombinase | false | Is Wild Type | false |
| description | ES cell line = R1 ((129X1/SvJ x 129S1/Sv)F1-Kitl+) or TL1 (129S6/SvEvTac). |
| molecularNote | A 7 kb genomic fragment containing exon 4 was replaced with a neomycin selection cassette. The deleted sequences encode the conserved dibasic proteolytic cleavage site between the pro- and mature regions of the encoded protein. In situ hybridization experiments on sections of testis of homozygous male mice confirmed that no detectable transcript was produced from this allele. |