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Allele : Bmp8b<tm1Blh> bone morphogenetic protein 8b; targeted mutation 1, Brigid L Hogan

Primary Identifier  MGI:1857954 Allele Type  Targeted
Attribute String  Null/knockout Gene  Bmp8b
Transmission  Germline Strain of Origin  129/Sv
Is Recombinase  false Is Wild Type  false
description  ES cell line = R1 ((129X1/SvJ x 129S1/Sv)F1-Kitl+) or TL1 (129S6/SvEvTac).
molecularNote  A 7 kb genomic fragment containing exon 4 was replaced with a neomycin selection cassette. The deleted sequences encode the conserved dibasic proteolytic cleavage site between the pro- and mature regions of the encoded protein. In situ hybridization experiments on sections of testis of homozygous male mice confirmed that no detectable transcript was produced from this allele.
  • mutations:
  • Insertion,
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

11 Publication categories