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Allele : Apex1<tm1Djc> apurinic/apyrimidinic endonuclease 1; targeted mutation 1, David J Chen

Primary Identifier  MGI:1857955 Allele Type  Targeted
Attribute String  Null/knockout Gene  Apex1
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
description  Homozygous mutant embryos proceed to embryonic day 6.5 - 7 with normal morphology and can be genotyped by PCR from day 9.5 embryo stages before their lethality. Pre-implantation blastocysts are gamma ionizing radiation sensitive (J:50702).
molecularNote  Exon 2, intron 2, exon 3 and part of intron 3 were replaced by a neomycin resistance cassette.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Ape/Ref<->,
  • Ape/Ref<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

8 Publication categories