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Allele : Pnliprp2<tm1Gru> pancreatic lipase-related protein 2; targeted mutation 1, Michael J Grusby

Primary Identifier  MGI:1857970 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Pnliprp2
Transmission  Germline Strain of Origin  129S2/SvPas
Is Recombinase  false Is Wild Type  false
molecularNote  The gene was disrupted by the introduction of a lacZ-neo cassette into the fourth exon via homologous recombination. Immunohistochemistry of acinar cells from pancreas of homozygous mutant animals did not detect protein product, and was positive for beta-galactosidase activity. RNase protection assay detected faint transcript (5% of wild-type signal) in adult homozygous mutant animals thought to be a chimeric transcript incorporating the lacZneo sequence.
  • mutations:
  • Insertion
  • synonyms:
  • PLRP2<->,
  • Pnliprp2<tm1Lowe>,
  • PLRP2<->,
  • Pnliprp2<tm1Lowe>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

7 Publication categories