| First Author | Bradley DJ | Year | 1979 |
| Journal | Clin Exp Immunol | Volume | 37 |
| Issue | 1 | Pages | 7-14 |
| PubMed ID | 290436 | Mgi Jnum | J:6209 |
| Mgi Id | MGI:54686 | Citation | Bradley DJ, et al. (1979) Regulation of Leishmania populations within the host. III. Mapping of the locus controlling susceptibility to visceral leishmaniasis in the mouse. Clin Exp Immunol 37(1):7-14 |
| abstractText | Acute susceptibility of the mouse to Leishmania donovani is largely determined by a single locus designated Lsh. Linkage between the Lsh locus and the Chromosome 1 marker Id-1 was detected using several sets of recombinant inbred strains. Chromosome 1 linkage was confirmed in backcross generations using isoenzymes and a cytogenetic marker. The data indicate that the gene order is centromere-Lsh-Id-1-ln-Dip-1. The estimated recombination frequency between Lsh and Id-1 is 0.12 +/- 0.04. This mapping is away from the known histocompatibility loci. |