Primary Identifier | MGI:1857846 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Pitx2 |
Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | This allele is derived from Pitx2tm1Sac. Gene targeting was performed with a vector engineered to contain a loxP site downstream from exon 4 and a floxed neomycin cassette upstream of exon 4. Subsequent cre expression resulted in deletion of both the neo selection cassette and exon 4. This allele is a demonstrated to be a functional null. |