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Allele : Pitx2<tm2Sac> paired-like homeodomain transcription factor 2; targeted mutation 2, Sally A Camper

Primary Identifier  MGI:1857846 Allele Type  Targeted
Attribute String  Null/knockout Gene  Pitx2
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  This allele is derived from Pitx2tm1Sac. Gene targeting was performed with a vector engineered to contain a loxP site downstream from exon 4 and a floxed neomycin cassette upstream of exon 4. Subsequent cre expression resulted in deletion of both the neo selection cassette and exon 4. This allele is a demonstrated to be a functional null.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Pitx2<null>,
  • Pitx2<->,
  • Pitx2<->,
  • Pitx2<null>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

38 Publication categories