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Allele : Abca4<tm1Ght> ATP-binding cassette, sub-family A member 4; targeted mutation 1, Gabriel H Travis

Primary Identifier	MGI:1857860	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Abca4
Transmission	Germline	Strain of Origin	129S4/SvJae
Is Recombinase	false	Is Wild Type	false

molecularNote

Replacement of a 4 kb genomic fragment containing the promoter and first exon with a neomycin cassette. Immunoblot analysis of retinal homogenates failed to detect any protein in samples derived from homozygous mice.

mutations:
Intragenic deletion,
Insertion

cellLines:
Not Specified

synonyms:
abcr<->,
abcr<->

earliestPublication:
Weng J, et al. (1999) Insights into the function of Rim protein in photoreceptors and etiology of Stargardt's disease from the phenotype in abcr knockout mice. Cell 98(1):13-23

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

3 Carried By

0 Driven By

102 Publication categories

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