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Allele : Rara<tm2Ipc> retinoic acid receptor, alpha; targeted mutation 2, Pierre Chambon

Primary Identifier  MGI:1857867 Allele Type  Targeted
Attribute String  Null/knockout Gene  Rara
Transmission  Germline Strain of Origin  129S2/SvPas
Is Recombinase  false Is Wild Type  false
molecularNote  Insertion of a neomycin cassette into exon 3. This disruption selectively prevents the synthesis of the alpha 1 isoform. RNAase protection analysis indicated that the mRNA encoding the alpha 1 isoform was mutated in this allele, and the alpha 2 isoform was transcribed normally.
  • mutations:
  • Insertion
  • synonyms:
  • Raralpha1,
  • Raralpha1,
  • RaRalpha1-,
  • RaRalpha1-
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

7 Publication categories