Primary Identifier | MGI:1857867 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Rara |
Transmission | Germline | Strain of Origin | 129S2/SvPas |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Insertion of a neomycin cassette into exon 3. This disruption selectively prevents the synthesis of the alpha 1 isoform. RNAase protection analysis indicated that the mRNA encoding the alpha 1 isoform was mutated in this allele, and the alpha 2 isoform was transcribed normally. |