Primary Identifier | MGI:1857889 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Itgav |
Transmission | Germline | Strain of Origin | 129S2/SvPas |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A neomycin resistance cassette replaced a genomic fragment containing the first exon, which encodes the signal peptide and first 30 amino acids of the mature protein. No mature protein was detected by immunoprecipitation studies on the cell surface of E16 or neonate dermal fibroblasts derived from homozygous mice. |