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Allele : Cftr<tm3Bay> cystic fibrosis transmembrane conductance regulator; targeted mutation 3, Baylor College of Medicine
Primary Identifier  MGI:1857898 Allele Type  Targeted
Attribute String  Null/knockout Gene  Cftr
Transmission  Germline Strain of Origin  129S7/SvEvBrd-Hprt1<b-m2>
Is Recombinase  false Is Wild Type  false
molecularNote  Sequences in exon 2 were mutated (c.134_138CAGCT>AACGTC) to create an in-frame stop codon (p.S45*) and frameshift. A neomycin resistance gene cassette was inserted in reverse transcriptional orientation into intron 1 of the gene.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • cftr<m3Bay>,
  • cftr<m3Bay>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

7 Publication categories





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