| Primary Identifier | MGI:1857793 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Itga6 |
| Transmission | Germline | Strain of Origin | 129S2/SvPas |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A neomycin cassette replaced a genomic fragment that contains three coding exons of the gene corresponding to amino acids 62-194. Northern analysis of total RNA extracted from homozygous tissue showed the absence of full length message, and a presence of a truncated mRNA that should not yield a functional protein. Immunohistochemical analysis did not detect any protein produced from this allele in tissue sections derived from from homozygous embryos. |
