Primary Identifier | MGI:1857811 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Acox1 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A 1.3kb SstI-BamHI segment containing exons 8 and 9 was replaced with a neomycin selection cassette. The 3.8-kb transcript is undetectable in RNA derived from the livers of homozygous mice by Northern blot. Western blots and enzymatic assays confirmed the absence of functional protein in homozygous mice. |