Primary Identifier | MGI:1858022 | Allele Type | Targeted |
Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Met |
Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A wild-type human cDNA coding for the transmembrane and cytoplasmic domain of the receptor was inserted in-frame into mouse genomic sequences. The cDNA was followed by a neomycin resistance cassette. A fusion protein consisting of the murine extracellular domain fused to the human transmembrane and cytoplasmic domain is produced from this allele. This allele is a control for Mettm1Cpo and Mettm2Cpo. |