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Allele : Met<tm3Cpo> met proto-oncogene; targeted mutation 3, Carola Ponzetta

Primary Identifier  MGI:1858022 Allele Type  Targeted
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Met
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A wild-type human cDNA coding for the transmembrane and cytoplasmic domain of the receptor was inserted in-frame into mouse genomic sequences. The cDNA was followed by a neomycin resistance cassette. A fusion protein consisting of the murine extracellular domain fused to the human transmembrane and cytoplasmic domain is produced from this allele. This allele is a control for Mettm1Cpo and Mettm2Cpo.
  • mutations:
  • Insertion
  • synonyms:
  • Met<WT>,
  • Met<WT>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories