| Primary Identifier | MGI:1857995 | Allele Type | Targeted |
| Attribute String | Null/knockout, Reporter | Gene | Pou3f1 |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
| Is Recombinase | false | Is Wild Type | false |
| description | Mice homozygous for the mutation were dies soon afetr birth, but 2-4% survived with a runted phenotype and slight tremor. Immunochhemical analysis of sciatic nerves revealed postnatal developmental delays in Schwann Cell differentiation (J:34465). |
| molecularNote | A DNA fragment containing a LacZ-neomycin fusion gene preceded by an internal ribosome entry site (IRES) was inserted into the sequences encoding the DNA binding domain of the protein. Analysis of beta-galactosidase expression was the same as previously described Pou3f1 expression. |
