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Allele : Ctnnb1<tm1Mmt> catenin beta 1; targeted mutation 1, Makoto M Taketo
Primary Identifier  MGI:1858008 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Ctnnb1
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  Insertion of a PGK-neomycin resistance cassette introduced two loxP sites flanking exon 3 and the inserted cassette. Exon 3 contains phosphorylation target serine/threonine residues. Future deletion of exon 3 with cre recombinase would result in mRNA whose exons 2 and 4 are connected in frame.
  • mutations:
  • Insertion
  • synonyms:
  • Catnb<tm1Tak>,
  • Catnb<(Flox3>,
  • Catnb<tm1Tak>,
  • Ctnnb1<lox(ex3)>,
  • Catnb<lox(ex3)>,
  • GOF,
  • Ctnnb1<fl(ex3)>,
  • Ctnnb1<lox(ex3)>,
  • beta-cat<gof>,
  • Ctnnb1<ex3(loxP)>,
  • beta-cat<ex3>,
  • Ctnnb<llox(ex3)>,
  • Ctnnb1<(Ex3)fl>,
  • beta-cat<ex3>,
  • Ctnnb1<f(Ex3)>,
  • Ctnnb1<f(Ex3)>,
  • beta-cat<c.a.>,
  • beta-catenin<deltaex3>,
  • beta-catenin<loxEx3>,
  • Ctnnb1<(Ex3)fl>,
  • Ctnnb1<ex3(loxP)>,
  • beta-cat<loxEx3>,
  • Catnb<(Flox3>,
  • beta-catenin/loxP(ex3),
  • Ctnnb<llox(ex3)>,
  • beta-catenin<lox-ex3>,
  • Catnb<(ex3)fl>,
  • beta-cat<act>,
  • GOF,
  • Ctnnb1<fl(ex3)>,
  • Ctnnb1<iGOF>,
  • beta-cat<gof>,
  • BcatGOF,
  • Ctnnb1<ex3>,
  • BcatGOF,
  • beta-cat<loxEx3>,
  • Ctnnb1<ex3>,
  • beta-catenin<loxEx3>,
  • Ctnnb1<flx(ex3)>,
  • Ctnnb1<iGOF>,
  • beta-catenin<lox-ex3>,
  • Catnb<lox(ex3)>,
  • B-catenin<fl3>,
  • beta-catenin/loxP(ex3),
  • Ctnnb<lox(ex3)>,
  • Ctnnb1<flx(ex3)>,
  • beta-cat<act>,
  • beta-catenin<deltaex3>,
  • B-catenin<fl3>,
  • Ctnnb<lox(ex3)>,
  • beta-cat<c.a.>,
  • Catnb<(ex3)fl>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

5 Carried By

0 Driven By

543 Publication categories





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