| Primary Identifier | MGI:1860407 | Allele Type | Targeted |
| Attribute String | Null/knockout, Reporter | Gene | Thrb |
| Transmission | Germline | Strain of Origin | 129/Sv |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A cassette containing both a lacZ coding sequence and a neomycin resistance gene was used to replace exons 4 and 5 which code for the DNA binding domain. This insertion inactivates both the beta1 and beta2 isoforms. RT-PCR was used to demonstrate a lack of mRNA in homozygous mutant animals. |
