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Publication : Development of coloboma (Cm/+), a mutation with anterior lens adhesion.

First Author  Theiler K Year  1981
Journal  Anat Embryol (Berl) Volume  162
Issue  1 Pages  121-6
PubMed ID  7283170 Mgi Jnum  J:99768
Mgi Id  MGI:3583792 Doi  10.1007/BF00318098
Citation  Theiler K, et al. (1981) Development of coloboma (Cm/+), a mutation with anterior lens adhesion. Anat Embryol (Berl) 162(1):121-6
abstractText  A semidominant mutation in the laboratory mouse, Coloboma (Cm), is described. Coloboma is located on Chromosome 2, as is the similar mutation Dickie's small eye (Dey). Coloboma has a moderately reduced expressivity. The anterior chamber is usually present in Cm/+. Both Cm and Dey show delayed detachment of the lens vesicle and microphthalmia, and homozygotes of both apparently die early in pregnancy.
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