First Author | Theiler K | Year | 1981 |
Journal | Anat Embryol (Berl) | Volume | 162 |
Issue | 1 | Pages | 121-6 |
PubMed ID | 7283170 | Mgi Jnum | J:99768 |
Mgi Id | MGI:3583792 | Doi | 10.1007/BF00318098 |
Citation | Theiler K, et al. (1981) Development of coloboma (Cm/+), a mutation with anterior lens adhesion. Anat Embryol (Berl) 162(1):121-6 |
abstractText | A semidominant mutation in the laboratory mouse, Coloboma (Cm), is described. Coloboma is located on Chromosome 2, as is the similar mutation Dickie's small eye (Dey). Coloboma has a moderately reduced expressivity. The anterior chamber is usually present in Cm/+. Both Cm and Dey show delayed detachment of the lens vesicle and microphthalmia, and homozygotes of both apparently die early in pregnancy. |