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Publication : Electron microscopic and quantitative studies of cell necrosis in developing sensory ganglia in normal and Sprawling mutant mice.

First Author  Scaravilli F Year  1980
Journal  J Neurocytol Volume  9
Issue  3 Pages  373-80
PubMed ID  7441297 Mgi Jnum  J:130868
Mgi Id  MGI:3772487 Doi  10.1007/BF01181543
Citation  Scaravilli F, et al. (1980) Electron microscopic and quantitative studies of cell necrosis in developing sensory ganglia in normal and Sprawling mutant mice. J Neurocytol 9(3):373-80
abstractText  The percentage of neurons undergoing necrosis during foetal and early post-natal development in normal and Sprawling (Swl) mutant mice was determined. Two major peaks in the occurrence of necrosis were found at the 13th and the 19th foetal days in both groups of mice but at all stages the incidence was greater in Swl. Electron microscopically the first degenerative changes seemed to involve the perikaryon while many of the cells undergoing necrosis in Swl already showed the characteristic abnormalities previously described in that mutant.
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