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Allele : Adrb2<tm1Bkk> adrenergic receptor, beta 2; targeted mutation 1, Brian K Kobilka
Primary Identifier  MGI:1859675 Allele Type  Targeted
Attribute String  Null/knockout Gene  Adrb2
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin selection cassette was inserted into the sequence encoding the fourth transmembrane segment. This mutation is predicted to eliminate expression of a functional receptor. Ligand binding experiments confirmed that no functional receptor was expressed in the lung of homozygous mice.
  • mutations:
  • Insertion
  • synonyms:
  • Beta2-AR,
  • Beta2-KO,
  • Beta2-AR,
  • beta2AR<->,
  • Adrb2<->,
  • Adrb2<->,
  • Beta2-KO,
  • beta2AR<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

Trail: Allele

0 Driven By

169 Publication categories

Trail: Allele




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