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Allele : Cdh2<tm1Hyn> cadherin 2; targeted mutation 1, Richard Hynes

Primary Identifier	MGI:1861181	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Cdh2
Transmission	Germline	Strain of Origin	129S2/SvPas
Is Recombinase	false	Is Wild Type	false

molecularNote

A neomycin cassette was inserted into the exon 10, which encodes part of the extracellular domain of the protein. The protein was untectectable in Western blots of protein lysates derived from homozygous mutant embryos.

mutations:
Insertion

cellLines:
Not Specified

synonyms:
Cdh2<->,
N-cadherin<->,
N-cadherin<->,
Cdh2<->,
Ncad<neo>,
Ncad<neo>

earliestPublication:
Radice GL, et al. (1997) Developmental defects in mouse embryos lacking N-cadherin. Dev Biol 181(1):64-78

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

24 Publication categories

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