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Allele : Map3k14<aly> mitogen-activated protein kinase kinase kinase 14; alymphoplasia

Primary Identifier	MGI:1858522	Allele Type	Spontaneous
Gene	Map3k14	Inheritance Mode	Recessive
Strain of Origin	C57BL/6J	Is Recombinase	false
Is Wild Type	false

molecularNote

A G-to-A transition point mutation resulted in a replacement of a conserved glycine with an arginine at position 855 of the encoded protein (p.G855R).

mutations:
Single point mutation

synonyms:
nik<aly>,
aly,
aly,
nik<aly>

earliestPublication:
Miyawaki S, et al. (1994) A new mutation, aly, that induces a generalized lack of lymph nodes accompanied by immunodeficiency in mice. Eur J Immunol 24(2):429-34

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

3 Carried By

0 Driven By

104 Publication categories

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