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Allele : Traf6<tm1Mak> TNF receptor-associated factor 6; targeted mutation 1, Tak Mak

Primary Identifier  MGI:1859953 Allele Type  Targeted
Attribute String  Null/knockout Gene  Traf6
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  The insertion of a neomycin selection cassette disrupted the exon encoding the translation initiation codon and the first 100 residues, which constitute the amino terminal portion of the zinc RING finger domain. Western blot analysis of renal immunoprecipitates and total renal lysates showed an absence of protein in homozygous mutant mice.
  • mutations:
  • Insertion
  • synonyms:
  • TRAF6<->,
  • TRAF6<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

15 Publication categories