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Allele : Tnf<tm1Ljo> tumor necrosis factor; targeted mutation 1, Lloyd J Old
Primary Identifier  MGI:1860250 Allele Type  Targeted
Attribute String  Null/knockout Gene  Tnf
Inheritance Mode  Semidominant Transmission  Germline
Strain of Origin  129S1/Sv-Oca2<+> Tyr<+> Kitl<+> Is Recombinase  false
Is Wild Type  false
molecularNote  A phosphoglycerate kinase-neomycin cassette replaced nucleotides 3704-5364; this is a deletion of 2.2 kb containing the promoter region, transcription start site, and exons 1 and 2 of the gene. Lack of the protein was demonstrated functionally.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • TNF-,
  • TNFalpha ko,
  • TNF-,
  • TNFalpha ko
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

5 Carried By

0 Driven By

101 Publication categories





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