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Publication : Cilia, tubby mice, and obesity.

First Author  Mukhopadhyay S Year  2013
Journal  Cilia Volume  2
Pages  1 PubMed ID  23351214
Mgi Jnum  J:195052 Mgi Id  MGI:5476372
Doi  10.1186/2046-2530-2-1 Citation  Mukhopadhyay S, et al. (2013) Cilia, tubby mice, and obesity. Cilia 2(1):1
abstractText  ABSTRACT: Primary cilia have been previously linked to the central regulation of satiety. The tubby mouse is characterized by maturity-onset obesity and blindness. A recent paper demonstrates molecular defects in trafficking of ciliary GPCRs in the central neurons of tubby mice, underscoring the role of ciliary signaling in the pathogenesis of this monogenic obesity syndrome.
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